POTS, postural orthostatic tachycardia syndrome, is an autonomic nervous system disorder that affects blood flow in between 1 million and 3 million Americans, typically women and young adults. Those numbers are growing as POTS and other forms of dysautonomia have been diagnosed as long-term impacts from COVID-19. The symptoms include fainting spells, seizures, respiratory issues and digestive trouble.Nina Kikel-Coury, a graduate student in Professor Cody Smith's lab, suffers from POTS which placed her at a higher risk during the COVID-19 pandemic. She needed to remain completely isolated during the pandemic and could no longer work alongside others in her research lab. But the team rallied around her.Her lab mates designated hours when Nina could work alone, and they continued her experiments when she couldn’t be present sending results via email or FaceTime. With all this support, Nina made a scientific breakthrough, discovering a new cell in the heart—cardiac nexus glia—which may help explain and treat conditions like hers.“Identifying cardiac nexus glia could have a huge impact, not only with the neuroscience field but also the cardiovascular field,” she says. “Currently no one knows why dysautonomia occurs in a lot of people. And so personally it’s really exciting to know that maybe we’re just one step closer to figuring out the cause of dysautonomia, and in particular, long term down the road maybe even POTS.”Read more: https://go.nd.edu/ResearchThatMattersWWYFF
More from What Would You Fight For?
- 2:01Fighting for the Lives of ChildrenWhen your child is diagnosed with a rare, genetic disease, it feels like you’re rolling down a mountain, just waiting to hit rock bottom, says Doug Berns. When his daughter, Samantha, was diagnosed with Niemann-Pick Type C, an incurable, neurodegenerative disorder, he and his wife watched as Samantha’s energy depleted, her balance became shaky, and her laughter quieted.At Notre Dame, researchers in the Boler-Parseghian Center for Rare and Neglected Diseases seek to identify and advance treatments for a number of rare diseases, including Niemann-Pick Type C.For more information: http://ntrda.me/LivesofChildren
- 2:01Fighting to Walk AgainPerhaps no greater motivation exists in this world than hope. For the 450,000 Americans with spinal cord injuries, the hope that they can regain mobility, walk again, run again is often what pushes them through each therapy session. But those same patients often plateau in their recovery, and hope dwindles.Though he’s not a physician or physical therapist, Notre Dame engineering professor Jim Schmiedeler’s work may contribute to better success for these patients. In his locomotion and biomechanics lab, he uses tools from his biped robotics research to better understand the challenges spinal cord injuries present for those learning to walk again. By partnering with researchers at The Ohio State University, Schmiedeler can also test how lessons learned from experiments with the robots, which involve no risk to humans, can be translated into innovative therapeutic strategies that benefit patients. In doing so, he believes his work can help many of those individuals with a spinal cord injury to walk again.Read More: http://ntrda.me/WalkAgain
