POTS, postural orthostatic tachycardia syndrome, is an autonomic nervous system disorder that affects blood flow in between 1 million and 3 million Americans, typically women and young adults. Those numbers are growing as POTS and other forms of dysautonomia have been diagnosed as long-term impacts from COVID-19. The symptoms include fainting spells, seizures, respiratory issues and digestive trouble.Nina Kikel-Coury, a graduate student in Professor Cody Smith's lab, suffers from POTS which placed her at a higher risk during the COVID-19 pandemic. She needed to remain completely isolated during the pandemic and could no longer work alongside others in her research lab. But the team rallied around her.Her lab mates designated hours when Nina could work alone, and they continued her experiments when she couldn’t be present sending results via email or FaceTime. With all this support, Nina made a scientific breakthrough, discovering a new cell in the heart—cardiac nexus glia—which may help explain and treat conditions like hers.“Identifying cardiac nexus glia could have a huge impact, not only with the neuroscience field but also the cardiovascular field,” she says. “Currently no one knows why dysautonomia occurs in a lot of people. And so personally it’s really exciting to know that maybe we’re just one step closer to figuring out the cause of dysautonomia, and in particular, long term down the road maybe even POTS.”Read more: https://go.nd.edu/ResearchThatMattersWWYFF
More from What Would You Fight For?
- 2:01Fighting to Educate a Different Kind of LawyerSince 2008, the Notre Dame Law School has sent students to eastern Kentucky, one of the poorest regions in the country. The students offer pro bono legal services to those who could not afford them otherwise.In recent years, they’ve worked with hundreds of disabled residents who are victims of Eric Conn, a lawyer who committed the largest Social Security fraud in U.S. history. You may have seen the docu-series about him on Apple TV+. Many of the victims have lost their only source of income and are struggling to make ends meet.But this is more than a service trip. It’s an academic course in the school’s curriculum that shapes the way these students perceive and practice law. And it’s one of several experiential learning opportunities with similar, practical objectives.See how Notre Dame is educating a different kind of lawyer: https://go.nd.edu/EducateADifferentKindofLawyer
- 0:52What Would You Fight For? | 2022 SeasonThe University of Notre Dame’s award-winning “What Would You Fight For?” series showcases the work, scholarly achievements, and global impact of Notre Dame faculty, students, and alumni.These two-minute segments will air during home football game broadcast on NBC. They highlight the University’s proud moniker, the Fighting Irish, and tell the stories of the members of the Notre Dame family who fight to bring solutions to a world in need.
- 2:01Fighting for Literacy Across AmericaTeaching English at Oakland High in the late 1990s, Ernest Morrell faced the age-old problem of how to get modern students interested in a canon of long-dead writers and poets. He watched kids muddle through class, heads down, interest limited. Then one day, while teaching Beowulf, a student’s eyes lit up when he realized the story was similar to a popular rap song. That day, Professor Morrell saw a spark of joy, enthusiasm and engagement and wondered how he could give that spark to all his students.He started bringing in other contemporary tangents – pop culture references, movies, music – but without losing the basis in classic literature. His students were learning. They were engaged. And, most importantly, Professor Morrell says, they were learning to love school and love themselves.Since then, Professor Morrell has authored K-5 and 6-12 curricula which are being taught by schools in every state. He’s advocated for teaching that not only improves academic outcomes, but also personal and social ones. And he’s teaching Notre Dame undergraduates and ACE students to find that spark in their lives and the lives of those around them.Learn more: https://go.nd.edu/LiteracyAcrossAmericaWWYFF
- 2:01Fighting for our Military CommunityDuring Jayme Hentig’s career as an Army medic, he was comfortable caring for others every day. But in 2010, he went from caregiver to patient after an accident sent his armored vehicle into a rollover. As he grappled with a traumatic brain injury and struggled to regain his cognitive abilities, doctors eventually told him there were no more therapeutic options. But Jayme was undeterred and decided if there were no existing options, he would create them.After earning his undergraduate degree, Jayme came to Notre Dame to pursue a doctorate in biology. Working with zebrafish, he was able to better understand how and why brain cells regenerate. After graduation he will continue to study traumatic brain injuries in active-duty service members and veterans as a postdoctoral fellow at the National Institutes of Health.Learn more: https://go.nd.edu/MilitaryCommunityFF
- 2:01Fighting for the Dignity of IndependenceIn 2014, Shawn Sexton ’88 was diagnosed with bulbar onset sporadic ALS. Realizing he would gradually lose his ability to walk, communicate and eat, he and his son, John, set out to create opportunities for independence. Together they designed EyeDrive, an assistive technology that allows Shawn to adjust and drive his wheelchair using eye gaze technology. EyeDrive is one of three current solutions provided by John’s startup, LifeDrive, which also provides voice- and caregiver-controlled solutions.John is now a senior at Notre Dame and a participant in the Grand Challenges Scholars Program, which, along with the IDEA Center, has helped move LifeDrive from an at-home project to an expanded medical device company. John continues to lead its progress to commercialization and distribution, and he hopes it will soon help other patients like his dad find more independence.“To try and get this to patients by the time that we graduate is daunting and challenging, but it pales in comparison to the needs of those patients that we’re trying to serve,” John says. He explains that getting LifeDrive to patients is so important because not only does it give them technology and independence, but it gives them hope. That hope, he says, can be life-giving.Learn more: https://go.nd.edu/DignityOfIndependenceFF
- 2:01Fighting Infectious Disease at its SourceSecond only to malaria as the most devastating parasitic disease in the world, schistosomiasis annually infects 200 million people and claims 200,000 lives. Another 800 million people are at risk, predominantly across Africa, eastern Latin America and southeast Asia. While there are existing cures, reinfection rates are very high.Jason Rohr, the Ludmilla F., Stephen J. and Robert T. Galla College Professor of Biological Sciences and chair of the biology department, works in more than 20 Senegalese villages alongside local partners such as Espoir Pour La Santé (EPLS) and Station d’Innovation Aquacole to address issues related to schistosomiasis.The infection is caused by a parasite that resides on snails, which live in weedy rivers and lakes where people drink, bathe, and launder. Rohr realized the number of parasites would decrease if the number of snails decreased, which could be achieved if the weeds decreased. Working alongside local partners in St. Louis, Senegal, they started weeding the water. Immediately, disease reinfection rates fell. What’s more, the villagers used the weeds to feed livestock and as compost fertilizer to increase food production. This became an added incentive for the community to remove the vegetation. A simple solution helped solve problems in disease, energy, and food scarcity.Learn more: https://go.nd.edu/InfectiousDiseaseWWYFF
