In a given year, around 60,000 Americans experience advanced heart failure, and many of them need a heart transplant to survive. While 10,000 hearts are donated each year, nearly 7,000 of them are not used. About half are not healthy enough, and though the other half are fully functional, those hearts can’t get to the recipient within the four-hour window recommended for effective transplants.But thanks to a partnership between Notre Dame engineering professor Pinar Zorlutuna and the University of Florida, there may be a way to extend that window to eight hours, which would allow many more donated hearts to reach patients. Professor Zorlutuna has created a novel and ethical way of converting adult blood and skin cells to functioning, beating heart muscle. These heart cells are being used to test an improved preservative solution that lengthens a donated heart’s lifespan. This safe and inexpensive platform has allowed for treatments to be tested without using very precious donated hearts, and initial studies show promise for these solutions.Learn more: https://ntrda.me/FFHumanHeart
Learn more about Professor Zorlatuna: https://go.nd.edu/WomenLeadZorlatuna
More from What Would You Fight For?
- 2:01Fighting for Better Cancer DetectionIn the United States alone, there are nearly 240,000 breast cancer diagnoses each year, and one in eight women will develop breast cancer at some point in her lifetime. To date, mammograms are the best diagnostic technology for breast cancer. A mammogram’s ability to detect tumors at early stages has made breast cancer one of the most treatable forms of cancer, but there are still almost 50,000 missed diagnoses every year.For many women, that missed diagnosis comes from having dense breast tissue which prohibits clear results from a basic mammogram. Notre Dame professor Ryan Roeder is working to reduce the number of missed diagnoses in dense breast tissue by using gold nanoparticles. The nanoparticles can be injected into the breast and attach to indicators of cancer, like microcalcifications. Because gold is a heavy metal, in an X-ray or mammogram it will be seen clearly, even in dense tissue.Roeder’s project is far from the finish line, but optimism in this fight against breast cancer is high. With luck, partnerships and persistence, the best way to think pink may involve thinking gold.
- 2:07Fighting to Protect the InnocentThrough collaboration with the National Immigrant Justice Center, Notre Dame law students are able to participate in an NIJC externship program allowing them to work on asylum cases of immigrants entering the United States.Law School alumnae Stephanie Torres and Christina Shakour took on the case of Maria and Ariel, immigrants from El Salvador seeking a safer life after receiving threats of violence from gangs. The team worked up to 30 hours a week on top of their course work to help the family in need. In total, they filed more than 300 pages of documentation to prove that the family qualified for asylum. After hours of preparation, Shakour and Torres presented the case before Immigration Court and obtained asylum for Maria and Ariel in the United States.*Because the well-being of Maria's daughters is still in jeopardy in El Salvador, and because gang retaliation could still occur in the U.S., actors were used in this What Would You Fight For video.*
