In a given year, around 60,000 Americans experience advanced heart failure, and many of them need a heart transplant to survive. While 10,000 hearts are donated each year, nearly 7,000 of them are not used. About half are not healthy enough, and though the other half are fully functional, those hearts can’t get to the recipient within the four-hour window recommended for effective transplants.But thanks to a partnership between Notre Dame engineering professor Pinar Zorlutuna and the University of Florida, there may be a way to extend that window to eight hours, which would allow many more donated hearts to reach patients. Professor Zorlutuna has created a novel and ethical way of converting adult blood and skin cells to functioning, beating heart muscle. These heart cells are being used to test an improved preservative solution that lengthens a donated heart’s lifespan. This safe and inexpensive platform has allowed for treatments to be tested without using very precious donated hearts, and initial studies show promise for these solutions.Learn more: https://ntrda.me/FFHumanHeart
Learn more about Professor Zorlatuna: https://go.nd.edu/WomenLeadZorlatuna
More from What Would You Fight For?
- 2:01Fighting For Freedom of ThoughtWhen the Soviet Union collapsed, democracies in post-Soviet territories was fragile, and corruption ruled government, business and education. People were killed for speaking out and demanding justice. But there was a beacon of hope — Catholic universities. Because of their spirit of independence, these institutions could teach radical ideas like human dignity, freedom of speech, transparency and justice.Since 2003, the Nanovic Institute for European Studies at the University of Notre Dame has made a commitment to Catholic education in Eastern Europe bringing together administrators and faculty at seven universities to build bridges that will help them speak truth to power.Learn more: https://ntrda.me/FreedomofThought
- 2:03Fighting to Protect Our CountrySince 1993, the International Atomic Energy Agency has tracked 2,500 trafficking cases of nuclear material. While there has yet to be a detonation of a dirty bomb, the threat remains present. In the unlikely event of a nuclear attack on American soil, Notre Dame engineering professor Antonio Simonetti makes one thing clear: The perpetrator could and would be found.Simonetti is a geochemist who specializes in characterizing the chemical and isotopic composition of materials. Traditionally, that involves studying rocks and minerals, which Simonetti did for many years. In 2011 he pivoted to assess nuclear materials like trinitite at the request of National Nuclear Security Agency. In that role, he used laser ablation-inductively coupled plasma mass spectrometry (ICP-MS) to study blast melt from the first atomic bomb test in New Mexico in 1945 and precisely identified where remnants of plutonium fuel resided after the explosion.More: http://ntrda.me/FTProtectOurCountry
- 2:08Fighting Mosquito-borne Diseases
- 2:01Fighting to End PovertyIn Dandora, Kenya, a sprawling neighborhood in Nairobi, housing for 250,000 people is built around the city’s largest dumpsite. Life near a large trash heap exposes the population to problems ranging from illness to unemployment to extreme poverty.Many of the town’s residents spend their days wading in the trash, looking for bits of aluminum and plastic that they can exchange for a few dollars to support their family. Others, typically women, run roadside stands selling goods like fruit or medications. For many families, the profits from these microenterprises are the only way to put food on the table or to send children to school.Notre Dame and its Ford Program in Human Development Studies and Solidarity have been invested in Dandora for several years. Research projects and a Holy Cross parish have taken root. In speaking with the local population about their needs, the Ford Program asked a trio of Notre Dame economists — Wyatt Brooks, Kevin Donovan and Terry Johnson — to come to Dandora to explore problems surrounding unemployment.For more information: http://ntrda.me/FFEndPoverty
- 2:01Fighting for the Lives of ChildrenWhen your child is diagnosed with a rare, genetic disease, it feels like you’re rolling down a mountain, just waiting to hit rock bottom, says Doug Berns. When his daughter, Samantha, was diagnosed with Niemann-Pick Type C, an incurable, neurodegenerative disorder, he and his wife watched as Samantha’s energy depleted, her balance became shaky, and her laughter quieted.At Notre Dame, researchers in the Boler-Parseghian Center for Rare and Neglected Diseases seek to identify and advance treatments for a number of rare diseases, including Niemann-Pick Type C.For more information: http://ntrda.me/LivesofChildren
- 2:01Fighting to Walk AgainPerhaps no greater motivation exists in this world than hope. For the 450,000 Americans with spinal cord injuries, the hope that they can regain mobility, walk again, run again is often what pushes them through each therapy session. But those same patients often plateau in their recovery, and hope dwindles.Though he’s not a physician or physical therapist, Notre Dame engineering professor Jim Schmiedeler’s work may contribute to better success for these patients. In his locomotion and biomechanics lab, he uses tools from his biped robotics research to better understand the challenges spinal cord injuries present for those learning to walk again. By partnering with researchers at The Ohio State University, Schmiedeler can also test how lessons learned from experiments with the robots, which involve no risk to humans, can be translated into innovative therapeutic strategies that benefit patients. In doing so, he believes his work can help many of those individuals with a spinal cord injury to walk again.Read More: http://ntrda.me/WalkAgain
