Fighting Infectious Disease at its Source
Second only to malaria as the most devastating parasitic disease in the world, schistosomiasis annually infects 200 million people and claims 200,000 lives. Another 800 million people are at risk, predominantly across Africa, eastern Latin America and southeast Asia. While there are existing cures, reinfection rates are very high.Jason Rohr, the Ludmilla F., Stephen J. and Robert T. Galla College Professor of Biological Sciences and chair of the biology department, works in more than 20 Senegalese villages alongside local partners such as Espoir Pour La Santé (EPLS) and Station d’Innovation Aquacole to address issues related to schistosomiasis.The infection is caused by a parasite that resides on snails, which live in weedy rivers and lakes where people drink, bathe, and launder. Rohr realized the number of parasites would decrease if the number of snails decreased, which could be achieved if the weeds decreased. Working alongside local partners in St. Louis, Senegal, they started weeding the water. Immediately, disease reinfection rates fell. What’s more, the villagers used the weeds to feed livestock and as compost fertilizer to increase food production. This became an added incentive for the community to remove the vegetation. A simple solution helped solve problems in disease, energy, and food scarcity.Learn more: https://go.nd.edu/InfectiousDiseaseWWYFF
More from What Would You Fight For?
- 2:01Fighting For Compassion in MedicineFor a new medical resident, or even an experienced doctor, the emotional toll of the job can be overwhelming. Dominic Vachon ’80, ’85 M.Div., a practicing psychologist, experienced it firsthand—he found himself burnt out, stretched thin, and emotionally detached from his patients, so eight years ago he came to Notre Dame determined to understand the scientific implications of compassion from a biological, neuroscientific, and psychological perspective. Now, Vachon is Notre Dame’s John G. Sheedy, M.D., Director of the Ruth M. Hillebrand Center for Compassionate Care in Medicine and is training the next generation of doctors to root their practice in compassion. “Compassion is essential for patient care and it's essential for the well-being of the clinician. The two go hand in hand,” Vachon explains. He underscores that compassion isn’t sentimentality, but is instead an applied use of skills, knowledge, and communication to foster successful doctor-patient relationships. Sam Grewe ’21 has seen the impact of compassion from the other side of medicine. When he was 13 years old, Grewe developed osteosarcoma, a type of bone cancer, and was eventually required to amputate one of his legs. As a teenager undergoing treatments, surgeries, and therapies, he said his doctors, especially the ones who took the time to explain, who provided comfort, and who gave him a sense of agency, motivated him to work hard and do well. Now, he’s a Paralympic high jumper and is planning to attend medical school next fall.More: https://go.nd.edu/CompassionInMedicine
- 2:01Fighting to Build on TraditionWhen Dot Teso, the president of St. Michael Indian School on the Navajo Nation, wanted to expand her campus, she turned to Notre Dame’s School of Architecture. After years of partnering with Notre Dame’s ACE program and American Indian Catholic Schools Network, she had witnessed Notre Dame’s commitment to Catholic education, and she was confident the architecture faculty and students would bring the same commitment to design.She, along with Deswood Etsitty ’93, invited a group of undergraduates to the campus in Arizona to learn about Navajo culture, to meet the community members, and to start designing the campus’ first new building, a gym where the community can congregate.The students are trained in Classicism and were eager to incorporate Navajo art, culture and values into their designs. Several of those designs will serve as the basis of the school’s upcoming construction.Read more: https://go.nd.edu/BuildOnTradition
- 2:01Fighting to Go Faster and Farther than Ever Thought PossibleIn 1882, Notre Dame student Albert Zahm built a rudimentary wind tunnel to study wing and propeller shapes. He went on to launch glider experiments from the roof of LaFortune and to write influential aeronautics papers in the early days of human flight.In 2018, Notre Dame continued its commitment to aeronautics by building the country’s largest quiet Mach 6 wind tunnel. The tunnel, designed by engineering professor Thomas Juliano, will allow researchers to perform experiments on temperature distribution, aerodynamic designs and propulsion systems for hypersonic aircraft. Information gathered could influence everything from faster airplanes to outer space reconnaissance.Read more: https://go.nd.edu/FasterandFarther
- 2:01Fighting to Understand the Scientific Impact of CommunityOn a dusty plain in Amboseli National Park in Kenya, Notre Dame professor Beth Archie stands watching baboons and taking notes. The data she collects is part of one of the world’s longest-running primate studies in existence.The study has followed the same community of baboons since 1971, and its data can reveal important information about human health. Because studies of this tenure are nearly impossible in humans, the baboons, who share a 94 percent genetic similarity with us, can tell us a lot about ourselves. These days, Archie’s lab seeks to answer questions about how being part of a community impacts health. The results point to improved immune responses, resilience to trauma, and longer lifespans.Read more:
- 2:01Fighting to Protect the BraveWhen firefighters run into a burning building, they know the dangers associated with their job. But new research suggests firefighters are at risk before they ever leave the firehouse.Using a spectroscopic technique and the St. Andre particle accelerator, Notre Dame professor Graham Peaslee has found alarming amounts of polyfluoroalkyl substances (PFAS) in firefighter gear. These chemicals have been linked to elevated rates of cancer and have also been found in fast-food wrappers, cosmetics, drinking water, carpet and flame retardants. He is now working to test many years of new and used gear to better assess the risks for firefighters.Professor Peaslee’s work in this area has encouraged several companies to reduce or eliminate PFAS, and the EPA and state legislators have also made policy changes. He hopes this new study will make firefighters safer, so they can continue to keep all of us safe.
- 2:00Fighting to Help Others Walk AgainMarissa Koscielski ’17, ’18 M.S., was in eighth grade when she was told she wouldn’t walk again. A gymnastics accident and spinal mass had left her paralyzed on the left side from the waist down. But she was determined and decided to build her own device to facilitate her rehabilitation. With strings and tape and bits of therapy equipment, Marissa repurposed a walker to help her slowly walk, and then run, once more.The experience taught her there is a gap in the tools and technology available for those rehabilitating from severe injuries, illnesses, and amputations. After completing her undergraduate degree at Notre Dame, she entered the ESTEEM program—a one-year master of science program focused on entrepreneurship and commercialization—and launched Enlighten Mobility, a startup that designs specialized rehab technology. Today, all of the company’s employees are Notre Dame graduates. Enlighten Mobility has since created its first product, a gait trainer largely based on the one Marissa designed for herself. The walker and other upcoming inventions are enabling Marissa to help others walk again.Learn more: https://go.nd.edu/HelpOthersWalkAgain