From reaction to resolution: The future of allergy treatment
Twelve-year-old Lauren Eglite was thrilled to attend a Notre Dame football game with her father, Erik, in 2017, even though her acute peanut allergy demands constant vigilance.
She was even more excited when the stadium’s brand-new video board aired an NBC Fighting For story about Basar Bilgicer’s research into blocking peanut allergens from triggering immune system overreactions. She asked her father, a drug company executive and Notre Dame business school alumnus, if this might be an opportunity to get involved with a solution to a condition that had complicated her life since childhood.
“I remember to this day her looking at that screen and turning to me,” Dr. Erik Eglite said. “She said, ‘Daddy, can I meet him? I really want to do something about it.’ This kid actually did that.”
It was a bold request, but Bilgicer didn’t hesitate after Dr. Eglite reached out. The Notre Dame professor of chemical and biomolecular engineering invited the whole Eglite family to his lab and explained his complex research in overwhelming detail.
The coincidence of that video playing to the right audience of two has led to immense mutual benefits. Nearly eight years later, Bilgicer and Eglite have partnered to form a company called Artin Immunology that aims to turn Bilgicer’s peanut allergy research into a blockbuster drug.
Latest ND NewsWire
- First impressions count: How babies are talked about during ultrasounds impacts parent perceptions, caregiving relationshipPsychologist Kaylin Hill studied the impact of a parent’s first impression of their baby during an ultrasound exam. The words used by the medical professional to describe the baby (positive or negative) influence how the parents perceive their baby, relate to them after they're born and even how that child behaves as a toddler. The research has broad implications for how we train medical professionals to interact with expectant parents, as well as how we care for parents during the perinatal period when they are most susceptible to depression.
- Researchers at Notre Dame detect ‘forever chemicals’ in reusable feminine hygiene productsWhen a reporter with the Sierra Club magazine asked Graham Peaslee, a physicist at the University of Notre Dame, to test several different samples of unused menstrual underwear for per- and polyfluoroalkyl substances (PFAS) in 2019, the results fueled concern over chemical exposure in feminine hygiene products — which ultimately ended up in a $5 million lawsuit against the period and incontinence underwear brand Thinx. Then in 2023, the New York Times asked Peaslee to test 44 additional period and incontinence products for PFAS, a class of toxic fluorinated compounds inherently repellent to oil, water, soil and stains, and known as “forever chemicals” for their exceptionally strong chemical and thermal stability. Measurable PFAS were found in some layers of many of the products tested — some low enough to suggest the chemicals may have transferred off packaging materials, while others contained higher concentrations, suggesting the chemicals were intentionally used during the manufacturing process. In the meantime, another group of researchers published a study that found PFAS in single-use period products, leading Peaslee and his lab to widen their investigation into all sorts of reusable feminine hygiene products — often viewed as an eco-friendly option by consumers. Now, the results of that study have been published in Environmental Science & Technology Letters.
- Smarter tools for policymakers: Notre Dame researchers target urban carbon emissions, building by buildingCarbon emissions continue to increase at record levels, fueling climate instability and worsening air quality conditions for billions in cities worldwide. Yet despite global commitments to carbon neutrality, urban policymakers still struggle to implement effective mitigation strategies at the city scale. Now, researchers at Notre Dame’s School of Architecture, the College of Engineering and the Lucy Family Institute for Data & Society are working to reduce carbon emissions through advanced simulations and a novel artificial intelligence-driven tool, EcoSphere.
- Notre Dame Lead Innovation Team partners with local WIC program to identify, prevent lead poisoning in childrenB.A.B.E. store “shoppers” now have something new to help their families: free lead screening kits offered by the University of Notre Dame’s Lead Innovation Team.
- Vatican honors Martin and Carmel Naughton with papal awardThe late Pope Francis, in one of his last acts, conferred the honour of the Order of Saint Gregory the Great upon Carmel and Martin Naughton, Trustee Emeritus of the University of Notre Dame. The papal honor is in recognition of the Naughtons’ outstanding philanthropy in the areas of education and the arts, particularly in the provision of philanthropic support and scholarships to Catholic education at the University of Notre Dame and Kylemore Abbey, and in their transformative contributions to higher education in Ireland.
- Brain tumor growth patterns may help inform patient care managementAssistant Professor Meenal Datta (University of Notre Dame/Wes Evard) A team of researchers from the University of Notre Dame, Harvard Medical School/Massachusetts General Hospital, and Boston University has developed a technique for measuring a brain tumor’s mechanical force and a new model to estimate how much brain tissue a patient has lost.
