The Chemical Synthesis and Drug Discovery (CSDD) Facility supports translational biomedical research by providing expertise that enables the preparation of small molecules for use in hit verification, lead development, and midsize scale up. It supports the preparation of biological probes (affinity or fluorescently tagged), active pharmaceutical agents as experimental controls, and small chemical libraries for structure-activity relationships and the optimization of pharmacological properties.

In addition, the CSDD provides organizational oversight for the Notre Dame Chemical Compound Collection, which has more than 20,000 unique chemical entities. It is available to researchers from the Notre Dame research community, other academic institutions, and industry.

Related Link: drugdiscovery.nd.edu